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ADA updates Standards of Care in Diabetes

The updates, which were released by the American Diabetes Association (ADA) in June, cover therapy to delay onset of type 1 diabetes and screening for nonalcoholic fatty liver disease.
https://diabetes.acponline.org/archives/2023/07/14/1.htm
14 Jul 2023

Afternoon physical activity linked to greater HbA1c reduction than other times of day

A secondary analysis of the Look AHEAD (Action for Health in Diabetes) study found that participants who performed more moderate to vigorous physical activity in the afternoon versus other times of day had the greatest reduction in HbA1c compared to those who were inactive.
https://diabetes.acponline.org/archives/2023/06/09/2.htm
9 Jun 2023

Vitamin D may reduce risk of progression to diabetes from prediabetes

In adults with prediabetes, high-dose vitamin D was associated with a 12% to 15% reduced risk for diabetes compared with placebo, a systematic review and meta-analysis found, but an editorial cautioned about the uncertain risk of adverse effects.
https://diabetes.acponline.org/archives/2023/02/10/3.htm
10 Feb 2023

Spotlight on diabetes drug class comparisons

A large trial compared insulin, a sulfonylurea, a glucagon-like peptide-1 (GLP-1) receptor agonist, and a dipeptidyl peptidase-4 inhibitor as second-line therapy, while a modeling study considered GLP-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors as first-line agents.
https://diabetes.acponline.org/archives/2022/10/14/5.htm
14 Oct 2022

Overnight glucose associated with next-day functioning in adults with type 1 diabetes

More variation in overnight glucose levels and time spent above and below glucose targets were associated with adverse changes in measures of next-day function, including attention, sedentary time, and engagement in demanding activities, a study found.
https://diabetes.acponline.org/archives/2023/03/10/2.htm
10 Mar 2023

Social, medical intervention improved glycemic control in rural patients with diabetes

A population health team assessed patients' medical, behavioral, and social needs with annual health risk assessments and partnered with community organizations to improve their access to food, transportation, and medicine.
https://diabetes.acponline.org/archives/2023/03/10/3.htm
10 Mar 2023

HbA1c levels above 9% may be associated with higher dementia risk

A cohort study found higher dementia risk among type 2 diabetes patients ages 50 years and older whose HbA1c levels were usually in the 9% to 10% or 10% and above range compared to those with tighter glycemic control.
https://diabetes.acponline.org/archives/2023/05/12/2.htm
12 May 2023

ACP Journal Club: SGLT-2 inhibitors reduce adverse renal and CV outcomes in patients with or without diabetes

The results of this meta-analysis of sodium-glucose cotransporter-2 (SGLT-2) inhibitors highlight the opportunity for internists, nephrologists, endocrinologists, and cardiologists to collaborate to expand use of the drug class, an ACP Journal Club commentary said.
https://diabetes.acponline.org/archives/2023/03/10/7.htm
10 Mar 2023

GLP-1 receptor agonists associated with better primary CV prevention vs. DPP-4 inhibitors

A retrospective study compared cardiovascular (CV) outcomes among patients adding glucagon-like peptide-1 (GLP-1) receptor agonists, sodium-glucose cotransporter-2 inhibitors, or dipeptidyl peptidase-4 (DPP-4) inhibitors to metformin, sulfonylurea, or insulin treatment alone or in combination.
https://diabetes.acponline.org/archives/2023/05/12/3.htm
12 May 2023

Younger patients often ration insulin due to cost, study finds

Data from the 2021 National Health Interview Survey indicate that one in five patients younger than age 65 years, who would not be eligible for the $35 monthly Medicare price cap, have skipped or reduced insulin doses or put off buying the drug to save money.
https://diabetes.acponline.org/archives/2023/04/14/3.htm
14 Apr 2023

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