Search results for "From ACP Journal Club"
In patients with type 2 diabetes and CV disease, empagliflozin reduced a composite of CV events at 3.1 years
An industry-funded trial found that those who took empagliflozin had lower rates of mortality, including from cardiovascular (CV) events, than those on placebo. A commentary in ACP Journal Club called the trial results fascinating but said they are not yet sufficient to change practice.
https://diabetes.acponline.org/archives/2016/02/12/5.htm
12 Feb 2016
Some antimicrobials increased admissions and ED visits for hypoglycemia in older users of glipizide or glyburide
A study of Texas Medicare patients who took either glipizide or glyburide found that those who were also prescribed certain antibiotics had a much higher rate of hypoglycemic events than those taking an antibiotic not expected to interact with sulfonylureas.
https://diabetes.acponline.org/archives/2015/03/13/7.htm
13 Mar 2015
DPP-4 inhibitors are less effective than metformin for reducing hemoglobin A1c
A meta-analysis of randomized controlled trials comparing dipeptidyl peptidase-4 (DPP-4) inhibitors to metformin and other drugs found that DPP-4 monotherapy is less effective.
https://diabetes.acponline.org/archives/2012/08/10/7.htm
10 Aug 2012
Bariatric surgery improved HbA1c at 5 y more than intensive medical care alone in obese patients with T2DM
A commentary considers the industry-funded STAMPEDE trial, in which obese patients with type 2 diabetes were randomly assigned to intensive medical therapy alone or intensive medical therapy plus Roux-en-Y gastric bypass or sleeve gastrectomy.
https://diabetes.acponline.org/archives/2017/06/09/6.htm
9 Jun 2017
Metformin reduced CV events compared with glipizide in patients with type 2 diabetes and CAD
A multicenter randomized controlled trial of Chinese patients with type 2 diabetes and coronary artery disease found that metformin reduced cardiovascular events more than glipizide at 5 years.
https://diabetes.acponline.org/archives/2013/05/10/10.htm
10 May 2013
Review: Bariatric surgery increases weight loss and diabetes remission more than nonsurgical treatment
A meta-analysis of 11 randomized, controlled trials found that bariatric surgery improved several health and diabetes outcomes more than nonsurgical treatment.
https://diabetes.acponline.org/archives/2014/02/14/6.htm
14 Feb 2014
Review: Bariatric surgery improves weight and glycemia in nonmorbidly obese adults with diabetes
A review of 3 randomized controlled trials found that surgical treatment increased weight loss and improved diabetes-related outcomes more than nonsurgical treatment in moderately obese patients.
https://diabetes.acponline.org/archives/2013/11/08/7.htm
8 Nov 2013
Meta-analysis: Self-monitoring in non-insulin-treated type 2 diabetes improved HbA1c by 0.25%
A meta-analysis of randomized controlled trials of patients with non–insulin-treated type 2 diabetes found that six months of self-monitoring blood glucose reduced hemoglobin A1c levels by 0.25% more than usual care.
https://diabetes.acponline.org/archives/2012/07/13/8.htm
13 Jul 2012
Review: Quality improvement strategies reduce HbA1c, LDL cholesterol, and BP in diabetes
Researchers reviewed more than 140 randomized trials of quality improvement (QI) strategies for managing adult patients with diabetes.
https://diabetes.acponline.org/archives/2012/11/09/8.htm
9 Nov 2012
Hypoglycemia was associated with increased mortality in ICU patients regardless of glucose control strategy
A post hoc analysis of the NICE-SUGAR trial that included about 6,000 ICU patients compared intensive glucose control (targeting blood glucose levels of 81 to 108 mg/dL) and conventional glucose control (targeting levels ≤180 mg/dL).
https://diabetes.acponline.org/archives/2013/02/08/6.htm
8 Feb 2013